Diabetic Foot Ulceration

pathology  

DIABETES

There are many types of diabetes, the most common being:

 

Type I
  • Accounts for approximately 10% of patients with diabetes
  • Characterized by total absence or very minimal presence of insulin
  • The condition is managed by injecting insulin or receiving insulin via a pump

 

Type II
  • Accounts for approximately 85% of patients with diabetes
  • Characterized by either a lack of insulin or insulin resistance
  •  This form of diabetes can be managed by one or a combination of:
    • Diet
    • Healthy exercise
    • Medication in a tablet e.g. Biguanides (Metformin) / Sulfonylurea (Gliclazide
    • Medication via injections e.g. GLP-1 receptor agonists (Exenatide)
    • Insulin

     

DIABETIC FOOT ULCERATION DEFINITION

  • Non / slow healing wound present on the foot below the ankle
  • Extends below the dermis
  • Present in a person with diabetes
  • Present alongside Neuropathy &/or Ischemia

 

INCIDENCE

  • Incidence rate of DFU between 1.0 – 3.6%
  • Prevalence rate of 5%
  • 15% of patients with diabetes will have a foot ulcer, however recent studies suggest a lifetime risk of 25%
  • Mortality rates following major amputation suggested to be up to 70% within 5 years.”